Elucidating the role of nicotinamide N-methyltransferase-p53 axis in the progression of chronic kidney disease

Background Chronic kidney disease (CKD) is a significant global health issue characterized by progressive loss of kidney function. Renal interstitial fibrosis (TIF) is a common feature of CKD, but current treatments are seldom effective in reversing TIF. Nicotinamide N-methyltransferase (NNMT) has b...

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Bibliographic Details
Main Authors: Xin Zhen, Yuxiang Sun, Hongchun Lin, Yuebo Huang, Tianwei Liu, Yuanqing Li, Hui Peng
Format: Article
Language:English
Published: PeerJ Inc. 2023-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/16301.pdf