The role of TDP-43 protein in amyotrophic lateral sclerosis

The role of TDP-43 protein in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease where both upper and lower motoneurons are damaged. Even though the pathogenesis of ALS is unclear, the TDP-43 aggregations and non-nuclear localization may be crucial to understanding this process. Despite intensive res...

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Bibliographic Details
Main Authors: Piotr Włodarczyk, Mikołaj Witczak, Agnieszka Gajewska, Tomasz Chady, Igor Piotrowski
Format: Article
Language:English
Published: Poznan University of Medical Sciences 2022-12-01
Series:Journal of Medical Science
Subjects:
Amyotrophic lateral sclerosis
ALS
TDP-43
SINE
Antisense oligonucleotides
Chaperones
Online Access:https://jms.ump.edu.pl/index.php/JMS/article/view/710

Internet

https://jms.ump.edu.pl/index.php/JMS/article/view/710

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