MAL Inhibits the Production of HIV-1 Particles by Sequestering Gag to Intracellular Endosomal Compartments

MAL Inhibits the Production of HIV-1 Particles by Sequestering Gag to Intracellular Endosomal Compartments

The host innate immune response is the first line of defense against human immunodeficiency virus (HIV) infection. The type I interferon (IFN) response is a robust anti-viral response that induces the transcription of several IFN-stimulated genes (ISGs). However, the effects of ISGs, particularly on...

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Bibliographic Details
Main Authors: Kei Miyakawa, Mayuko Nishi, Sundararaj Stanleyraj Jeremiah, Yuko Morikawa, Akihide Ryo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Virology
Subjects:
HIV-1
interferon-stimulated genes
Gag
antiviral immunity
innate immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2022.836125/full

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https://www.frontiersin.org/articles/10.3389/fviro.2022.836125/full

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