Development and Validation of an HPLC-MS/MS Method for the Quantitative Determination of Etmaben in Human Blood Plasma

Development and Validation of an HPLC-MS/MS Method for the Quantitative Determination of Etmaben in Human Blood Plasma

Introduction. Etmaben is a promising drug for the treatment of cardiovascular diseases, widely studied in preclinical studies. In order to conduct phase I clinical trials, it is necessary to develop a bioanalytical method for the quantitative determination of etmaben in human blood plasma.Aim. The a...

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Bibliographic Details
Main Authors: P. K. Karnakova, T. N. Komarov, O. A. Archakova, D. Yu. Ivkin, E. S. Vetrova, I. I. Terninko, I. E. Shohin, I. A. Narkevich
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2024-03-01
Series:Разработка и регистрация лекарственных средств
Subjects:
etmaben
hplc-ms/ms
development
validation
blood plasma
quantitative determination
pharmacokinetics
Online Access:https://www.pharmjournal.ru/jour/article/view/1768

Internet

https://www.pharmjournal.ru/jour/article/view/1768

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