Single-cell analysis reveals changes in BCG vaccine-injected mice modeling tuberculous meningitis brain infection

Summary: Tuberculous meningitis (TBM) is the most severe and deadly manifestation of tuberculosis. Neurological complications are observed in up to 50% of patients affected. Here, attenuated Mycobacterium bovis are injected into the cerebellum of mice, and histopathological images and cultured colon...

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Bibliographic Details
Main Authors: Xiaolin Zhang, Zhangyan Zhao, Qingguo Wu, Lei Wang, Liqun Li, Mei Wang, Yang Ren, Lei Pan, Haicheng Tang, Feng Li
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723001882