Direct and/or Indirect Roles for SUMO in Modulating Alpha-Synuclein Toxicity

α-Synuclein inclusion bodies are a pathological hallmark of several neurodegenerative diseases, including Parkinson’s disease, and contain aggregated α-synuclein and a variety of recruited factors, including protein chaperones, proteasome components, ubiquitin and the small ubiquitin-like modifier,...

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Bibliographic Details
Main Authors: Shamini Vijayakumaran, Mathew B. Wong, Helma Antony, Dean L. Pountney
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/5/3/1697