Evaluation of therapeutic use of a combination of pentoxifylline and vitamin E in radiation-induced renal fibrosis

Abstract Radiation-induced renal fibrosis (RIRF) is a progressive, irreversible condition causing chronic kidney disease. Pentoxifylline (PTX) and vitamin E may mitigate radiation-induced damage and fibrosis. This study assesses their effectiveness. We used four groups, each with six rats: radiation...

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Bibliographic Details
Main Authors: Volkan Demircan, Caglar Guzel, Gulistan Sanem Sarıbas, Serap Catlı Dinc, Serhat Cetin, Ozlem Gulbahar, Petek Erpolat, Cigdem Elmas, Huseyin Bora
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-57850-0