Is SARS-CoV-2 Neutralized More Effectively by IgM and IgA than IgG Having the Same Fab Region?

Recently, recombinant monoclonal antibodies (mAbs) of three Ig isotypes (IgG, IgA, and IgM) sharing the same anti-spike protein Fab region were developed; we evaluated their neutralizing abilities using a pseudo-typed lentivirus coated with the SARS-CoV-2 spike protein and ACE2-transfected Crandell–...

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Bibliographic Details
Main Authors: Yalcin Pisil, Zafer Yazici, Hisatoshi Shida, Tomoyuki Miura
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/10/6/751