Modification effect of ideal cardiovascular health metrics on genetic association with incident heart failure in the China Kadoorie Biobank and the UK Biobank

Modification effect of ideal cardiovascular health metrics on genetic association with incident heart failure in the China Kadoorie Biobank and the UK Biobank

Abstract Background Both genetic and cardiovascular factors contribute to the risk of developing heart failure (HF), but whether idea cardiovascular health metrics (ICVHMs) offset the genetic association with incident HF remains unclear. Objectives To investigate the genetic association with inciden...

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Bibliographic Details
Main Authors: Ruotong Yang, Jun Lv, Canqing Yu, Yu Guo, Pei Pei, Ninghao Huang, Ling Yang, Iona Y. Millwood, Robin G. Walters, Yiping Chen, Huaidong Du, Ran Tao, Junshi Chen, Zhengming Chen, Robert Clarke, Tao Huang, Liming Li, on behalf of the China Kadoorie Biobank Collaborative Group
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Medicine
Subjects:
Heart failure
Ideal cardiovascular health metrics
Genetic risk
Online Access:https://doi.org/10.1186/s12916-021-02122-1

Internet

https://doi.org/10.1186/s12916-021-02122-1

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