Accelerated inflammatory aging in Alzheimer’s disease and its relation to amyloid, tau, and cognition

Abstract It is unclear how pathological aging of the inflammatory system relates to Alzheimer’s disease (AD). We tested whether age-related inflammatory changes in cerebrospinal fluid (CSF) and plasma exist across different stages of AD, and whether such changes related to AD pathology. Linear regre...

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Bibliographic Details
Main Authors: Nicholas C. Cullen, A nders Mälarstig, Erik Stomrud, Oskar Hansson, Niklas Mattsson-Carlgren
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81705-7