Molecular dynamics simulations of amyloid-β peptides in heterogeneous environments

Alzheimer’s disease is thought to be caused by the aggregation of amyloid-β (Aβ) peptides. Their aggregation is accelerated at hydrophilic/hydrophobic interfaces such as the air–water interface and the surface of monosialotetrahexosylganglioside (GM1) clusters on neuronal cell membranes. In this rev...

Full description

Bibliographic Details
Main Authors: Yuhei Tachi, Satoru G. Itoh, Hisashi Okumura
Format: Article
Language:English
Published: The Biophysical Society of Japan 2022-04-01
Series:Biophysics and Physicobiology
Subjects:
Online Access:https://doi.org/10.2142/biophysico.bppb-v19.0010