Development and Evaluation of <sup>99m</sup>Tc Tricarbonyl Complexes Derived from Flutamide with Affinity for Androgen Receptor

Development and Evaluation of <sup>99m</sup>Tc Tricarbonyl Complexes Derived from Flutamide with Affinity for Androgen Receptor

With the objective to develop a potential <sup>99m</sup>Tc radiopharmaceutical for imaging the androgen receptor (AR) in prostate cancer, four ligands bearing the same pharmacophore derived from the AR antagonist flutamide were prepared, labeled with <sup>99m</sup>Tc, and the...

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Bibliographic Details
Main Authors: María Elena Cardoso, Paula Decuadra, Maia Zeni, Agustín Delfino, Emilia Tejería, Fátima Coppe, Juan Manuel Mesa, Grysette Daher, Javier Giglio, Gonzalo Carrau, Daniela Gamenara, Omar Alonso, Mariella Terán, Ana Rey
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
<sup>99m</sup>Tc
prostate cancer
androgen receptor
Online Access:https://www.mdpi.com/1420-3049/28/2/820

Internet

https://www.mdpi.com/1420-3049/28/2/820

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