Time- and Dose-Dependent Effects of Ionizing Irradiation on the Membrane Expression of Hsp70 on Glioma Cells

Time- and Dose-Dependent Effects of Ionizing Irradiation on the Membrane Expression of Hsp70 on Glioma Cells

The major stress-inducible protein Hsp70 (HSPA1A) is overexpressed in the cytosol of many highly aggressive tumor cells including glioblastoma multiforme and presented on their plasma membrane. Depending on its intracellular or membrane localization, Hsp70 either promotes tumor growth or serves as a...

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Bibliographic Details
Main Authors: Helena Fellinger, Stefan Stangl, Alicia Hernandez Schnelzer, Melissa Schwab, Tommaso Di Genio, Marija Pieper, Caroline Werner, Maxim Shevtsov, Bernhard Haller, Gabriele Multhoff
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
radiotherapy
glioblastoma
membrane Hsp70
dose- and time-kinetics
NK cell-based therapy
Online Access:https://www.mdpi.com/2073-4409/9/4/912

Internet

https://www.mdpi.com/2073-4409/9/4/912

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