Intestinal alkaline phosphatase (IAP, IAP Enhancer) attenuates intestinal inflammation and alleviates insulin resistance

Intestinal alkaline phosphatase (IAP, IAP Enhancer) attenuates intestinal inflammation and alleviates insulin resistance

In this study, we investigated the effects of intestinal alkaline phosphatase (IAP) in controlled intestinal inflammation and alleviated associated insulin resistance (IR). We also explored the possible underlying molecular mechanisms, showed the preventive effect of IAP on IR in vivo, and verified...

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Bibliographic Details
Main Authors: Chenzhe Gao, Marwa Yagoub Farag Koko, Mingxing Ding, Weichen Hong, Jianping Li, Na Dong, Mizhou Hui
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
intestinal inflammation
intestinal alkaline phosphatase
lipopolysaccharide
adenosine
dephosphorylation
signalling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.927272/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.927272/full

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