Tryptophan-5-HT pathway disorder was uncovered in the olfactory bulb of a depression mice model by metabolomic analysis

Tryptophan-5-HT pathway disorder was uncovered in the olfactory bulb of a depression mice model by metabolomic analysis

Major depression (MD) is a severe mental illness that creates a heavy social burden, and the potential molecular mechanisms remain largely unknown. Lots of research demonstrate that the olfactory bulb is associated with MD. Recently, gas chromatography-mass spectrometry-based metabolomic studies on...

Full description

Bibliographic Details
Main Authors: Guanghui Chen, Siqi Zhou, Qiang Chen, Mengmeng Liu, Meixue Dong, Jiabao Hou, Benhong Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
major depression
metabolomic
olfactory bulb
tryptophan hydroxylase
chronic mild stress
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.965697/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.965697/full

Similar Items