Cyanoacetohydrazide linked to 1,2,3-triazole derivatives: a new class of α-glucosidase inhibitors

Abstract In this work, a novel series of cyanoacetohydrazide linked to 1,2,3-triazoles (9a–n) were designed and synthesized to be evaluated for their anti-α-glucosidase activity, focusing on the fact that α-glucosidase inhibitors have played a significant role in the management of type 2 diabetes me...

Full description

Bibliographic Details
Main Authors: Aida Iraji, Diba Shareghi-Brojeni, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Tahmineh Akbarzadeh, Mina Saeedi
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11771-y