Early over expression of messenger RNA for multiple genes, including insulin, in the Pancreatic Lymph Nodes of NOD mice is associated with Islet Autoimmunity

<p>Abstract</p> <p>Background</p> <p>Autoimmune diabetes (T1D) onset is preceded by a long inflammatory process directed against the insulin-secreting β cells of the pancreas. Deciphering the early autoimmune mechanisms represents a challenge due to the absence of clini...

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Bibliographic Details
Main Authors: Eisenbarth George, Miao Dongmei, Osorio y Fortea José, Regnault Béatrice, Melanitou Evie
Format: Article
Language:English
Published: BMC 2009-10-01
Series:BMC Medical Genomics
Online Access:http://www.biomedcentral.com/1755-8794/2/63