Exon junction complex shapes the m6A epitranscriptome

Exon junction complex shapes the m6A epitranscriptome

Here the authors show the exon junction complex (EJC) component, EIF4A3, locally restricts METTL3- mediated mRNA methylation at exon junctions to explain the observed widespread enrichment of m6A modification in 3’ untranslated regions.

Bibliographic Details
Main Authors: Xin Yang, Robinson Triboulet, Qi Liu, Erdem Sendinc, Richard I. Gregory
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35643-1

Internet

https://doi.org/10.1038/s41467-022-35643-1

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