Design of live-attenuated animal vaccines based on pseudorabies virus platform

Abstract Pseudorabies virus (PRV) is a double-stranded DNA virus with a genome approximating 150 kb in size. PRV contains many non-essential genes that can be replaced with genes encoding heterogenous antigens without affecting viral propagation. With the ability to induce cellular, humoral and muco...

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Bibliographic Details
Main Authors: Zhen Liu, Zhengjie Kong, Meng Chen, Yingli Shang
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Animal Diseases
Subjects:
Online Access:https://doi.org/10.1186/s44149-022-00044-w