Design of live-attenuated animal vaccines based on pseudorabies virus platform
Abstract Pseudorabies virus (PRV) is a double-stranded DNA virus with a genome approximating 150 kb in size. PRV contains many non-essential genes that can be replaced with genes encoding heterogenous antigens without affecting viral propagation. With the ability to induce cellular, humoral and muco...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2022-05-01
|
Series: | Animal Diseases |
Subjects: | |
Online Access: | https://doi.org/10.1186/s44149-022-00044-w |