Pharmacokinetics of PEGylated Gold Nanoparticles: In Vitro—In Vivo Correlation

Pharmacokinetics of PEGylated Gold Nanoparticles: In Vitro—In Vivo Correlation

Data suitable for assembling a physiologically-based pharmacokinetic (PBPK) model for nanoparticles (NPs) remain relatively scarce. Therefore, there is a trend in extrapolating the results of in vitro and in silico studies to in vivo nanoparticle hazard and risk assessment. To evaluate the reliabili...

Full description

Bibliographic Details
Main Authors: Tibor Dubaj, Katarina Kozics, Monika Sramkova, Alena Manova, Neus G. Bastús, Oscar H. Moriones, Yvonne Kohl, Maria Dusinska, Elise Runden-Pran, Victor Puntes, Andrew Nelson, Alena Gabelova, Peter Simon
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Nanomaterials
Subjects:
gold nanoparticles
human cell lines
pharmacokinetics
PBPK model
IVIVE
Online Access:https://www.mdpi.com/2079-4991/12/3/511

Internet

https://www.mdpi.com/2079-4991/12/3/511

Similar Items