Polo-like kinase 1 promotes Cdc42-induced actin polymerization for asymmetric division in oocytes

Polo-like kinase I (Plk1) is a highly conserved seronine/threonine kinase essential in meiosis and mitosis for spindle formation and cytokinesis. Here, through temporal application of Plk1 inhibitors, we identify a new role for Plk1 in the establishment of cortical polarity essential for highly asym...

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Bibliographic Details
Main Authors: Wai Shan Yuen, Qing Hua Zhang, Anne Bourdais, Deepak Adhikari, Guillaume Halet, John Carroll
Format: Article
Language:English
Published: The Royal Society 2023-03-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.220326