A 14-gene B-cell immune signature in early-stage triple-negative breast cancer (TNBC): a pooled analysis of seven studiesResearch in context

A 14-gene B-cell immune signature in early-stage triple-negative breast cancer (TNBC): a pooled analysis of seven studiesResearch in context

Summary: Background: Early-stage triple-negative breast cancer (TNBC) displays clinical and biological diversity. From a biological standpoint, immune infiltration plays a crucial role in TNBC prognosis. Currently, there is a lack of genomic tools aiding in treatment decisions for TNBC. This study...

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Bibliographic Details
Main Authors: Benedetta Conte, Fara Brasó-Maristany, Adela Rodríguez Hernández, Tomás Pascual, Guillermo Villacampa, Francesco Schettini, Maria J. Vidal Losada, Elia Seguí, Laura Angelats, Isabel Garcia-Fructuoso, Raquel Gómez-Bravo, Natàlia Lorman-Carbó, Laia Paré, Mercedes Marín-Aguilera, Olga Martínez-Sáez, Barbara Adamo, Esther Sanfeliu, Beatrice Fratini, Claudette Falato, Núria Chic, Ana Vivancos, Patricia Villagrasa, Johan Staaf, Joel S. Parker, Charles M. Perou, Aleix Prat
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:EBioMedicine
Subjects:
Triple-negative breast cancer (TNBC)
Pathological complete response (pCR)
Event-free survival (EFS)
Overall survival (OS)
B-cell/immunoglobulin signature (IGG)
Prognostic biomarkers
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424000781

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http://www.sciencedirect.com/science/article/pii/S2352396424000781

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