Pragmatic trials in primary care. Methodological challenges and solutions demonstrated by the DIAMOND-study

<p>Abstract</p> <p>Background</p> <p>Pragmatic randomised controlled trials are often used in primary care to evaluate the effect of a treatment strategy. In these trials it is difficult to achieve both high internal validity and high generalisability. This article will...

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Bibliographic Details
Main Authors: Samsom Melvin, de Wit Niek J, Numans Mattijs E, Laheij Robert JF, Muris Jean WM, Mujakovic Suhreta, van Marrewijk Corine J, Fransen Gerdine AJ, Jansen Jan BMJ, Knottnerus J André
Format: Article
Language:English
Published: BMC 2007-04-01
Series:BMC Medical Research Methodology
Online Access:http://www.biomedcentral.com/1471-2288/7/16