Molecular identification and functional characterization of IRF4 from common carp (Cyprinus carpio. L) in immune response: a negative regulator in the IFN and NF-κB signalling pathways
Abstract Background The interferon (IFN) regulatory factors (IRFs) were originally identified as transcription factors playing critical roles in the regulation of IFN-related genes in the signal pathway. In mammals, IRF4 plays a vital role in both the innate and adaptive immune system. This study ai...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-03-01
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Series: | BMC Veterinary Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12917-022-03205-8 |