Structural insights into human brain–gut peptide cholecystokinin receptors

Structural insights into human brain–gut peptide cholecystokinin receptors

Abstract The intestinal hormone and neuromodulator cholecystokinin (CCK) receptors CCK1R and CCK2R act as a signaling hub in brain–gut axis, mediating digestion, emotion, and memory regulation. CCK receptors exhibit distinct preferences for ligands in different posttranslational modification (PTM) s...

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Bibliographic Details
Main Authors: Yu Ding, Huibing Zhang, Yu-Ying Liao, Li-Nan Chen, Su-Yu Ji, Jiao Qin, Chunyou Mao, Dan-Dan Shen, Lin Lin, Hao Wang, Yan Zhang, Xiao-Ming Li
Format: Article
Language:English
Published: Nature Publishing Group 2022-06-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-022-00420-3

Internet

https://doi.org/10.1038/s41421-022-00420-3

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