Esketamine Improves Working Memory Impairment in Neuropathic Mice Through Hippocampal BDNF-TrkB Pathway

Esketamine Improves Working Memory Impairment in Neuropathic Mice Through Hippocampal BDNF-TrkB Pathway

Objective  To explore the effect of esketamine on working memory impairment in neuropathic mice and its underlying mechanism.  Methods  Fifty clean grade male C57BL/6J mice (2 months) were divided into 5 groups by random number table method: sham+saline (SN group), CCI+saline (CN group), CCI+esketam...

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Bibliographic Details
Main Authors: JIANG Yubin, WANG Xingming, ZHANG Yue, ZHOU Zhiqiang, YANG Jianjun
Format: Article
Language:zho
Published: Editorial Office of Medical Journal of Peking Union Medical College Hospital 2024-03-01
Series:Xiehe Yixue Zazhi
Subjects:
esketamine
neuropathic pain
working memory
hippocampus
Online Access:https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2023-0581

Internet

https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2023-0581

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