Transfixed by transgenics: how pathology assumptions are slowing progress in Alzheimer's disease and related dementia research

Model organisms of human diseases are invaluable tools for unraveling pathogenic mechanisms, identifying potential targets for drug development, and evaluating the therapeutic efficacy of candidates in preclinical trials. The utility of model organisms hinges upon their ability to faithfully replica...

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Bibliographic Details
Main Author: Luciano D'Adamio
Format: Article
Language:English
Published: Springer Nature 2023-11-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.15252/emmm.202318479