Acid-sensing ion channels contribute to the effect of extracellular acidosis on proliferation and migration of A549 cells

Acid-sensing ion channels, a proton-gated cation channel, can be activated by low extracellular pH and involved in pathogenesis of some tumors such as glioma and breast cancer. However, the role of acid-sensing ion channels in the growth of lung cancer cell is unclear. In this study, we investigated...

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Bibliographic Details
Main Authors: Yu Wu, Bo Gao, Qiu-Ju Xiong, Yu-Chan Wang, Da-Ke Huang, Wen-Ning Wu
Format: Article
Language:English
Published: IOS Press 2017-05-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317705750