Phage Cocktails with Daptomycin and Ampicillin Eradicates Biofilm-Embedded Multidrug-Resistant <i>Enterococcus faecium</i> with Preserved Phage Susceptibility

Phage Cocktails with Daptomycin and Ampicillin Eradicates Biofilm-Embedded Multidrug-Resistant <i>Enterococcus faecium</i> with Preserved Phage Susceptibility

Multidrug-resistant (MDR) <i>Enterococcus faecium</i> is a challenging nosocomial pathogen known to colonize medical device surfaces and form biofilms. Bacterio (phages) may constitute an emerging anti-infective option for refractory, biofilm-mediated infections. This study evaluates eig...

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Bibliographic Details
Main Authors: Ashlan J. Kunz Coyne, Kyle Stamper, Razieh Kebriaei, Dana J. Holger, Amer El Ghali, Taylor Morrisette, Biswajit Biswas, Melanie Wilson, Michael V. Deschenes, Gregory S. Canfield, Breck A. Duerkop, Cesar A. Arias, Michael J. Rybak
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Antibiotics
Subjects:
<i>Enterococcus faecium</i>
bacteriophage cocktails
bacteriophage-antibiotic combinations
daptomycin
beta-lactams
phage-antibiotic synergy
Online Access:https://www.mdpi.com/2079-6382/11/9/1175

Internet

https://www.mdpi.com/2079-6382/11/9/1175

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