Early-Life Exposure to Non-Absorbable Broad-Spectrum Antibiotics Affects the Dopamine Mesocorticolimbic Pathway of Adult Rats in a Sex-Dependent Manner

Early-Life Exposure to Non-Absorbable Broad-Spectrum Antibiotics Affects the Dopamine Mesocorticolimbic Pathway of Adult Rats in a Sex-Dependent Manner

Gut microbiota with a stable, rich, and diverse composition is associated with adequate postnatal brain development. Colonization of the infant’s gut begins at birth when parturition exposes the newborn to a set of maternal bacteria, increasing richness and diversity until one to two first years of...

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Bibliographic Details
Main Authors: Camila González-Arancibia, Victoria Collio, Francisco Silva-Olivares, Paula Montaña-Collao, Jonathan Martínez-Pinto, Marcela Julio-Pieper, Ramón Sotomayor-Zárate, Javier A. Bravo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
antibiotics
gut microbiota
dopamine
dopamine receptors
VTA
NAcc
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.837652/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.837652/full

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