The mutation landscape of multiple cancer predisposition genes in Chinese familial/hereditary breast cancer families

The mutation landscape of multiple cancer predisposition genes in Chinese familial/hereditary breast cancer families

Objective: Approximately 5%–10% of breast cancer (BC) patients display familial traits that are genetically inherited among the members of a family. The purpose of this study was to profile the germline mutations in 43 genes with different penetration rates and their correlations with phenotypic tra...

Full description

Bibliographic Details
Main Authors: Li Dong, Hailian Zhang, Huan Zhang, Yingnan Ye, Yanan Cheng, Lijuan Li, Lijuan Wei, Lei Han, Yandong Cao, Shixia Li, Xishan Hao, Juntian Liu, Jinpu Yu
Format: Article
Language:English
Published: China Anti-Cancer Association 2022-06-01
Series:Cancer Biology & Medicine
Subjects:
familial breast cancer
predisposition genes
dna damage repair genes
clinical features
Online Access:https://www.cancerbiomed.org/content/19/6/850

Internet

https://www.cancerbiomed.org/content/19/6/850

Similar Items