An ultra-short-acting benzodiazepine in thalamic nucleus reuniens undermines fear extinction via intermediation of hippocamposeptal circuits

An ultra-short-acting benzodiazepine in thalamic nucleus reuniens undermines fear extinction via intermediation of hippocamposeptal circuits

Abstract Benzodiazepines, commonly used for anxiolytics, hinder conditioned fear extinction, and the underlying circuit mechanisms are unclear. Utilizing remimazolam, an ultra-short-acting benzodiazepine, here we reveal its impact on the thalamic nucleus reuniens (RE) and interconnected hippocampose...

Full description

Bibliographic Details
Main Authors: Hoiyin Cheung, Tong-Zhou Yu, Xin Yi, Yan-Jiao Wu, Qi Wang, Xue Gu, Miao Xu, Meihua Cai, Wen Wen, Xin-Ni Li, Ying-Xiao Liu, Ying Sun, Jijian Zheng, Tian-Le Xu, Yan Luo, Ma-Zhong Zhang, Wei-Guang Li
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-06417-w

Internet

https://doi.org/10.1038/s42003-024-06417-w

Similar Items