PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome

PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome

Abstract Background Cohesin is an important structural regulator of the genome, regulating both three-dimensional genome organization and gene expression. The core cohesin trimer interacts with various HEAT repeat accessory subunits, yielding cohesin complexes of distinct compositions and potentiall...

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Bibliographic Details
Main Authors: Nicole L. Arruda, Audra F. Bryan, Jill M. Dowen
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Epigenetics & Chromatin
Subjects:
Cohesin
Genome
Localization
Gene expression
PDS5A
PDS5B
Online Access:https://doi.org/10.1186/s13072-022-00463-6

Internet

https://doi.org/10.1186/s13072-022-00463-6

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