Simvastatin combined with bone marrow mesenchymal stromal cells (BMSCs) improve burn wound healing by ameliorating angiogenesis through SDF-1α/CXCR4 pathway

Simvastatin combined with bone marrow mesenchymal stromal cells (BMSCs) improve burn wound healing by ameliorating angiogenesis through SDF-1α/CXCR4 pathway

<em><strong>Objective(s):</strong></em> Chemokines are wound mediators that promote angiogenesis during wound healing. We hypothesized that Simvastatin in combination with the bone marrow mesenchymal stromal cells (BMSCs) improve burn wound healing by ameliorating angiogenesi...

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Bibliographic Details
Main Authors: Javad Mohajer Ansari, Parisa Ramhormozi, Ronak Shabani, Hamidreza Pazoki-toroudi, Abazar Yari, Mahmood Barati, Mostafa Dahmardehei, Azar Babakhani, Maliheh Nobakht
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2020-06-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
angiogenesis
bone marrow mesenchymal stromal cells
c-x-c motif chemokine receptor 4
stromal drive factor-1α
simvastatin
wound healing
Online Access:http://ijbms.mums.ac.ir/article_15506_b3c872a59f0e5505dbe03964fc118a7d.pdf

Internet

http://ijbms.mums.ac.ir/article_15506_b3c872a59f0e5505dbe03964fc118a7d.pdf

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