Microdissected Tissue vs Tissue Slices—A Comparative Study of Tumor Explant Models Cultured On-Chip and Off-Chip

Microdissected Tissue vs Tissue Slices—A Comparative Study of Tumor Explant Models Cultured On-Chip and Off-Chip

Predicting patient responses to anticancer drugs is a major challenge both at the drug development stage and during cancer treatment. Tumor explant culture platforms (TECPs) preserve the native tissue architecture and are well-suited for drug response assays. However, tissue longevity in these model...

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Bibliographic Details
Main Authors: Dina Dorrigiv, Kayla Simeone, Laudine Communal, Jennifer Kendall-Dupont, Amélie St-Georges-Robillard, Benjamin Péant, Euridice Carmona, Anne-Marie Mes-Masson, Thomas Gervais
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
cancer treatment
drug screening assays
tumor explant culture platform
hypoxia
ex vivo model
Online Access:https://www.mdpi.com/2072-6694/13/16/4208

Internet

https://www.mdpi.com/2072-6694/13/16/4208

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