Effective Synthesis and Antifouling Activity of Dolastatin 16 Derivatives

Effective Synthesis and Antifouling Activity of Dolastatin 16 Derivatives

Some derivatives of dolastatin 16, a depsipeptide natural product first obtained from the sea hare <i>Dolabella auricularia</i>, were synthesized through second-generation synthesis of two unusual amino acids, dolaphenvaline and dolamethylleuine. The second-generation synthesis enabled d...

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Bibliographic Details
Main Authors: Loida O. Casalme, Keisuke Katayama, Yoshiki Hayakawa, Kensuke Nakamura, Arisa Yamauchi, Yasuyuki Nogata, Erina Yoshimura, Fuyuhiko Matsuda, Taiki Umezawa
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Marine Drugs
Subjects:
natural product
antifouling
dolastatin 16
peptide
<i>Amphibalanus amphitrite</i>
Online Access:https://www.mdpi.com/1660-3397/20/2/124

Internet

https://www.mdpi.com/1660-3397/20/2/124

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