Phosphodiesterases regulate BAY 41-2272-induced VASP phosphorylation in vascular smooth muscle cells

BAY 41-2272 (BAY), a stimulator of soluble guanylyl cyclase, increases cyclic nucleotides and inhibits proliferation of vascular smooth muscle cells (VSMCs). In this study, we elucidated mechanisms of action of BAY in its regulation of vasodilator-stimulated phosphoprotein (VASP) with an emphasis o...

Full description

Bibliographic Details
Main Authors: Shaquria P Adderley, Chintamani N Joshi, Danielle N Martin, David Anthony Tulis
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00010/full