Human beta-defensin 3 is up-regulated in cutaneous leprosy type 1 reactions.

BACKGROUND:Leprosy, a chronic granulomatous disease affecting the skin and nerves, is caused by Mycobacterium leprae (M. leprae). The type of leprosy developed depends upon the host immune response. Type 1 reactions (T1Rs), that complicate borderline and lepromatous leprosy, are due to an increase i...

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Bibliographic Details
Main Authors: Anna L Cogen, Stephen L Walker, Chrissy H Roberts, Deanna A Hagge, Kapil D Neupane, Saraswoti Khadge, Diana N J Lockwood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3486878?pdf=render