Extracellular Signal-Regulated Kinase 1 Alone Is Dispensable for Hyperoxia-Mediated Alveolar and Pulmonary Vascular Simplification in Neonatal Mice

Extracellular Signal-Regulated Kinase 1 Alone Is Dispensable for Hyperoxia-Mediated Alveolar and Pulmonary Vascular Simplification in Neonatal Mice

Bronchopulmonary dysplasia (BPD) is a morbid lung disease distinguished by lung alveolar and vascular simplification. Hyperoxia, an important BPD causative factor, increases extracellular signal-regulated kinases (ERK)-1/2 expression, whereas decreased lung endothelial cell <i>ERK2</i> e...

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Bibliographic Details
Main Authors: Renuka T. Menon, Shyam Thapa, Amrit Kumar Shrestha, Roberto Barrios, Binoy Shivanna
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Antioxidants
Subjects:
extracellular signal-regulated kinases 1 and 2
neonatal HPMECs
hydrogen peroxide
hyperoxia
bronchopulmonary dysplasia
Online Access:https://www.mdpi.com/2076-3921/11/6/1130

Internet

https://www.mdpi.com/2076-3921/11/6/1130

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