Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer

Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer

Abstract Background Genetically engineered mouse models (GEMMs) of cancer are powerful tools to study mechanisms of disease progression and therapy response, yet little is known about how these models respond to multimodality therapy used in patients. Radiation therapy (RT) is frequently used to tre...

Full description

Bibliographic Details
Main Authors: Daniel R. Schmidt, Iva Monique T. Gramatikov, Allison Sheen, Christopher L. Williams, Martina Hurwitz, Laura E. Dodge, Edward Holupka, W. S. Kiger, Milton R. Cornwall-Brady, Wei Huang, Howard H. Mak, Kathleen S Cormier, Charlene Condon, K. Dane Wittrup, Ömer H. Yilmaz, Mary Ann Stevenson, Julian D. Down, Scott R. Floyd, Jatin Roper, Matthew G. Vander Heiden
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-023-00336-3

Internet

https://doi.org/10.1038/s43856-023-00336-3

Similar Items