A stress-blinded Atf1 can fully assemble heterochromatin in a RNAi-independent minimal mat locus but impairs directionality of mat2/3 switching

Summary: The MAP kinase Sty1 phosphorylates and activates the transcription factor Atf1 in response to several stress conditions, which then shifts from a transcriptional repressor to an activator. Atf1 also participates in heterochromatin assembly at the mat locus, in combination with the RNA inter...

Full description

Bibliographic Details
Main Authors: Rodrigo Fraile, Laura Sánchez-Mir, Guillem Murciano-Julià, José Ayté, Elena Hidalgo
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222010926