Interleukin-25-Mediated-IL-17RB Upregulation Promotes Cutaneous Wound Healing in Diabetic Mice by Improving Endothelial Cell Functions

Interleukin-25-Mediated-IL-17RB Upregulation Promotes Cutaneous Wound Healing in Diabetic Mice by Improving Endothelial Cell Functions

Diabetic foot ulcer (DFU) frequently leads to non-traumatic amputation and finally even death. However, the mechanism of DFU is not fully understood. Interleukin 25 (IL-25), an alarmin cytokine that responds to tissue injury, has been reported to participate in tissue regeneration and maintaining gl...

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Bibliographic Details
Main Authors: Fang Zhang, Ye Liu, Shiqi Wang, Xin Yan, Yue Lin, Deyan Chen, Qian Tan, Zhiwei Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
IL-25
IL-17RB
diabetes mellitus
wound healing
endothelial cell functions
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.809755/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.809755/full

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