Chemotherapy‐Induced Senescence Reprogramming Promotes Nasopharyngeal Carcinoma Metastasis by circRNA‐Mediated PKR Activation

Chemotherapy‐Induced Senescence Reprogramming Promotes Nasopharyngeal Carcinoma Metastasis by circRNA‐Mediated PKR Activation

Abstract Senescence is associated with tumor metastasis and chemotherapy resistance, yet the mechanisms remain elusive. Here, it is identified that nasopharyngeal carcinoma (NPC) patients who developed distant metastasis are characterized by senescence phenotypes, in which circWDR37 is a key regulat...

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Bibliographic Details
Main Authors: Qian Li, Yu‐Heng Zhao, Cheng Xu, Ye‐Lin Liang, Yin Zhao, Qing‐Mei He, Jun‐Yan Li, Kai‐Lin Chen, Han Qiao, Na Liu, Jun Ma, Lei Chen, Ying‐Qin Li
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:Advanced Science
Subjects:
circWDR37
metastasis
NF‐κB
protein kinase R
senescence
Online Access:https://doi.org/10.1002/advs.202205668

Internet

https://doi.org/10.1002/advs.202205668

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