High-Throughput Identification of Adaptive Mutations in Experimentally Evolved Yeast Populations.
High-throughput sequencing has enabled genetic screens that can rapidly identify mutations that occur during experimental evolution. The presence of a mutation in an evolved lineage does not, however, constitute proof that the mutation is adaptive, given the well-known and widespread phenomenon of g...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-10-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC5065121?pdf=render |