Quantification of High-Molecular Weight Protein Platforms by AQUA Mass Spectrometry as Exemplified for the CD95 Death-Inducing Signaling Complex (DISC)

Quantification of High-Molecular Weight Protein Platforms by AQUA Mass Spectrometry as Exemplified for the CD95 Death-Inducing Signaling Complex (DISC)

Contemporary quantitative mass spectrometry provides fascinating opportunities in defining the stoichiometry of high-molecular weight complexes or multiprotein platforms. The composition stoichiometry of multiprotein platforms is a key to understand the regulation of complex signaling pathways and p...

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Bibliographic Details
Main Authors: Inna Lavrik, Uwe Warnken, Kolja Schleich, Martina Schnölzer
Format: Article
Language:English
Published: MDPI AG 2013-06-01
Series:Cells
Subjects:
CD95
DISC
apoptosis
DED
protein quantification
mass spectrometry
AQUA technique
protein platforms
Online Access:http://www.mdpi.com/2073-4409/2/3/476

Internet

http://www.mdpi.com/2073-4409/2/3/476

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