Watching the human retina breath in real time and the slowing of mitochondrial respiration with age

Abstract The retina has the greatest metabolic demand in the body particularly in dark adaptation when its sensitivity is enhanced. This requires elevated level of perfusion to sustain mitochondrial activity. However, mitochondrial performance declines with age leading to reduced adaptive ability. W...

Full description

Bibliographic Details
Main Authors: Pardis Kaynezhad, Ilias Tachtsidis, Sobha Sivaprasad, Glen Jeffery
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-32897-7