Conserved paradoxical relationships among the evolutionary, structural and expressional features of KRAB zinc-finger proteins reveal their special functional characteristics

Conserved paradoxical relationships among the evolutionary, structural and expressional features of KRAB zinc-finger proteins reveal their special functional characteristics

Abstract Background One striking feature of the large KRAB domain-containing zinc finger protein (KZFP) family is its rapid evolution, leading to hundreds of member genes with various origination time in a certain mammalian genome. However, a comprehensive genome-wide and across-taxa analysis of the...

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Bibliographic Details
Main Authors: Pan Shen, Aishi Xu, Yushan Hou, Huqiang Wang, Chao Gao, Fuchu He, Dong Yang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Molecular and Cell Biology
Subjects:
KZFP
Evolutionary age
Structure
Expression
Function
Online Access:https://doi.org/10.1186/s12860-021-00346-w

Internet

https://doi.org/10.1186/s12860-021-00346-w

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