Optimization of Sirius Red-Based Microplate Assay to Investigate Collagen Production In Vitro

Optimization of Sirius Red-Based Microplate Assay to Investigate Collagen Production In Vitro

Tissue fibrosis is characterized by chronic fibroblast activation and consequently excessive accumulation of collagen-rich extracellular matrix. In vitro microplate-based assays are essential to investigate the underlying mechanism and the effect of antifibrotic drugs. In this study, in the absence...

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Bibliographic Details
Main Authors: Csenge Szász, Domonkos Pap, Beáta Szebeni, Péter Bokrossy, László Őrfi, Attila J. Szabó, Ádám Vannay, Apor Veres-Székely
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
fibroblast
collagen
extracellular matrix
Sirius Red
functional
microplate
Online Access:https://www.mdpi.com/1422-0067/24/24/17435

Internet

https://www.mdpi.com/1422-0067/24/24/17435

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