The anti-cancer effect of betulinic acid in u937 human leukemia cells is mediated through ROS-dependent cell cycle arrest and apoptosis

Although previous studies have shown anti-cancer activity of betulinic acid (BA), a pentacyclic triterpenoid, against various cancer lines, the underlying molecular mechanisms are not well elucidated. In this study, we evaluated the mechanisms involved in the anti-cancer efficacy of BA in U937 human...

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Bibliographic Details
Main Authors: Cheol Park, Jin-Woo Jeong, Min Ho Han, Hyesook Lee, Gi-Young Kim, Soojung Jin, Jung-Ha Park, Hyun Ju Kwon, Byung Woo Kim, Yung Hyun Choi
Format: Article
Language:English
Published: Taylor & Francis Group 2021-03-01
Series:Animal Cells and Systems
Subjects:
Online Access:http://dx.doi.org/10.1080/19768354.2021.1915380