The anti-cancer effect of betulinic acid in u937 human leukemia cells is mediated through ROS-dependent cell cycle arrest and apoptosis
Although previous studies have shown anti-cancer activity of betulinic acid (BA), a pentacyclic triterpenoid, against various cancer lines, the underlying molecular mechanisms are not well elucidated. In this study, we evaluated the mechanisms involved in the anti-cancer efficacy of BA in U937 human...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2021-03-01
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Series: | Animal Cells and Systems |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/19768354.2021.1915380 |