yGPS-P: A Yeast-Based Peptidome Screen for Studying Quality Control-Associated Proteolysis

yGPS-P: A Yeast-Based Peptidome Screen for Studying Quality Control-Associated Proteolysis

Quality control-associated proteolysis (QCAP) is a fundamental mechanism that maintains cellular homeostasis by eliminating improperly folded proteins. In QCAP, the exposure of normally hidden <i>cis</i>-acting protein sequences, termed degrons, triggers misfolded protein ubiquitination,...

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Bibliographic Details
Main Authors: Bayan Mashahreh, Shir Armony, Tommer Ravid
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biomolecules
Subjects:
protein quality control
quality control-associated proteolysis
ubiquitin-proteasome system (UPS)
degronome
fluorescence-activated cell sorting (FACS)
next generation sequencing (NGS)
Online Access:https://www.mdpi.com/2218-273X/13/6/987

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https://www.mdpi.com/2218-273X/13/6/987

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